A blinded cohort study of patients with elevated CA125 levels (30–500 kU/L) and a pelvic mass, from the UK Ovarian Cancer Population Study (UKOPS), was performed by analysing a combined glycoform profile that comprised STn-CA125, ST-CA125, and STn-CA15-3 (the three best-performing glycoforms). Here, MUC16 is linked to ovarian cancer.