CRH and aortic stenosis: In multivariable analyses, LVEF was independently and negatively associated with the CRH score in all types of VHD (Additional file 1: Table S7), and was identified as the most important associated factor of cardio-renal-hepatic co-dysfunction in AS, AR, MR, TR, MVHD, as well as in total cohort (Additional file 1: Figure S9 and S10).