GCG and Hypoglycemia: In cases where the child is known to have hypoglycemia caused by hyperinsulinism and IV therapy is not immediately available, pharmacologic doses of glucagon (0.5–1 mg or 20–30 μg/kg) can be used as an alternative acute therapy, given either intramuscularly or subcutaneously, with an effect lasting up to 40–60 min allowing time for IV insertion [95].