A significant correlation with age was documented for the classical CSF AD biomarkers, namely Aβ42/40 ratio (r = -0.40, p < 0.001), t-tau (r = 0.28, p < 0.001), and p-tau (r = 0.27, p < 0.001), as well as for the candidate biomarkers: UCHL1 (r = 0.24, p < 0.001), FABP3 (r = 0.29, p < 0.001), PKM (r = 0.29, p < 0.001), and ALDO (r = 0.26, p < 0.001). This evidence concerns the gene PKM and Alzheimer disease.