SETDB1 and neoplasm: We collected publicly available H3K9me3 ChIP-seq data (GSE155972) in Setdb1 KO murine tumor cells9 and discovered 30936 Setdb1-dependent H3K9me3 peaks (Supplementary Fig. 6d), approximately 30% of which could be reduced by Phf8 depletion (Supplementary Fig. 6d, upper right).