Although SNAI1, ZEB1, and ZEB2 were not upregulated in RNA-seq data of Adh ALL patient samples (Figure 4D), they have putative roles in leukemia development/progression,48-50 and we observed SNAIL (SNAI1) and ZEB1 but not ZEB2 to be highly expressed in Adh leukemic cell lines (Figure 4F). The gene discussed is ZEB1; the disease is leukemia.