ERBB2 and ductal breast carcinoma in situ: Gallen meeting in 2011 (Table 3), we found that the proportions of the subtypes differed between those classified as “pure” DCIS and those classified as having an additional invasive component, in which the HER2-enriched subtype was the largest among those with an invasive component (p-value = 0.0169, Fisher's exact test).