Consistent with our observations of Angptl2 KO and Itgα5 KO tRCC lines, CKO tRCC mice also exhibited increased expression of H‐2Kb and TAP1 proteins in tumor lesions from kidney tissues relative to tRCC mice, whereas expression of JARID2 proteins localized to cell nuclei was decreased in CKO tRCC mice (Fig. S3). The gene discussed is ITGA5; the disease is renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.