ANGPTL2 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: To further examine functional consequences of enhanced MHC‐I expression and MHC‐I antigen processing in Angptl2‐deficient tRCC cells, we co‐cultured CD8+ OT‐I T cells, which express a T‐cell receptor specifically recognizing H‐2Kb‐bound SIINFEKL peptide, with control‐OVA, Angptl2 KO‐OVA, or Angptl2 KO cells (Fig. 2E).