ANGPTL2 and neoplasm: To investigate this possibility, we established Angptl2 KO tumor lines (Angptl2 KO1 and KO2) using the primary tRCC cell line R286 established from tumors of tRCC mice [19] (Fig. 2A) and assessed expression of antigen presentation‐related genes, such as MHC‐I (H2‐K1 and H2‐D1) and antigen presentation machinery‐related molecules (B2m, Tap2, and Tapbp) (Fig. 2B).