The monocyte‐related cytokines and chemokines in ischemic stroke include CCL2/CCR2, CCR4, CCR5, CD36, CX3CL1/CX3CR1, CXCL12(SDF‐1), LFA‐1/ICAM‐1, Ly6C, MMP‐2/9, NR4A1, P2X4R, P‐selectin, CD40L, TLR2/4, VCAM‐1/VLA‐4, and their functions are listed in Table 1 below. The gene discussed is CD40LG; the disease is ischemic stroke.