We harvested breast tumor cells from TetO-Kras/MMTV-rtTA transgenic mice (K) and TetO-Kras/TetO-Mad2/MMTV-rtTA mice (KM) and observed higher Foxm1 mRNA and protein levels in KM compared to K tumor cells (Fig. 3A, B). This evidence concerns the gene KRAS and breast neoplasm.