Of the remaining significantly increased or decreased proteins that are male reproductive tract-specific with infertile mouse models, 8 are testis-specific genes found significantly decreased in KO corpus (AKAP3, AKAP4, CAPZA3, CATSPER3, CCIN, GK2, H2AL2A, and RSPH6A) and 1 is a dual testis/epididymis-specific gene (OAZ3). The gene discussed is CATSPER3; the disease is Infertility.