Several protein targets have been reported as potential intracellular targets of GAA, mainly focused on anti-apoptotic proteins (B-Cell CLL/Lymphoma 2 (Bcl-2), Bcl-2-Like Protein 1 (Bcl-xL), Myeloid Cell Leukemia Sequence 1 (Mcl-1), and Apurinic/Apyrimidinic Endodeoxyribonuclease 1 (APEX1))29–31. Here, APEX1 is linked to B-cell chronic lymphocytic leukemia.