The “Hot” tumor feature of C1 and C2 subtypes was analyzed with IFN-γ, Merck 18, CD8, PD-L1, T-cell dysfunction score, T-cell exclusion score, MDSC score, CAF score, and TAM.M2 score using the TIDE tool in the TCGA-LIHC datasets. This evidence concerns the gene IFNG and neoplasm.