As a further indication of the emerging role of astrocytes in PD pathophysiology (Booth et al., 2017; Wang et al., 2021) and in agreement with post-mortem findings in the CPu of PD patients (Di Maio et al., 2023), we found lower ASCT1 levels in the rPut of MPTP-treated monkeys compared to controls. This evidence concerns the gene SLC1A4 and Parkinson disease.