SOD1 and amyotrophic lateral sclerosis: Finally, we identified two distinct molecular signatures across C9-ALS-FTSD (n = 10), sporadic ALS (sALS) (n = 18) and SOD1-ALS (n = 5) cohorts, as well as in publicly available frontal cortex RNA sequencing data from independent C9-ALS and sALS cohorts.26