mQTLs of CpG sites cg06639488 (EFNA1), cg12101586 (CYP1A1) and cg14142171 (HLA‐L) was validated by eQTLs at specific cancer tissues, and cg07932199 (ATXN2) provided colocalization evidence of both methylation and susceptibility to multiple cancers. The gene discussed is CYP1A1; the disease is cancer.