CD4 and asthma: • Lymphocytes:↓Infiltration in asthma↑CD3+ T cells and CD4+ T cells; ↑Increase CD4+/CD8+ ratio↓CD8+ T↑Th1/Th2 ratio in asthma; ↓Th17/Treg balance in asthma• Antibody: ↑IgA, IgM, IgG; ↓IgE• Macrophages: ↓Infiltration; ↑Phagocytosis• Neutrophils: ↓Infiltration in asthma• Eosinophils: ↓Infiltration in asthma