Clinical studies revealed that Huaier increased the proportion of CD3+ and CD4+ T cells in peripheral blood in cancer patients receiving chemotherapy (37, 61–63, 72, 73); HQH, the compound preparation of Huaier, has also been claimed to raise serum levels of CD3+ and CD4+ T lymphocytes in pediatric patients suffering primary nephrotic syndrome (74) and severe Mycoplasma pneumonia (13). This evidence concerns the gene CD4 and cancer.