The PCR results in rat serum show that, compared with control group samples, the expression levels of COMMD9 and CSF3R were significantly decreased from rats with two sepsis model (LPS group=model1, CLP group=model2) (Figures 7D, E), and the expression level of NUB1 was significantly increased (Figure 7F). The gene discussed is COMMD9; the disease is Sepsis.