GAL and lymphoma: Incubation at 37°C for 2 h of lymphoma cells presenting α-gal epitopes with the patient’s macrophages in the presence of autologous anti-Gal resulted in extensive uptake of the tumor cells by the macrophages, whereas the original tumor cells lacking α-gal epitopes were not phagocytosed by the macrophages (Figure 7B) (Manches et al., 2005).