The use of NIR fluorescence and luciferase bioluminescence imaging was also successful in another NIR-PIT study targeting CD47 in human bladder cancer by transfecting 639V cell lines with GFP-luciferase in mouse xenograft models.96 In this study, NIR fluorescence reached its peak 1 day after injection, indicating that the max. This evidence concerns the gene CD47 and urinary bladder carcinoma.