TNF and pancreatic neoplasm: We performed cytokine array profiling in pancreatic tumor lysates obtained from vehicle and Uro A-treated PKT mice which demonstrated a significant reduction in proinflammatory/immunosuppressive factors including GMCSF, CXCL-1, IL1α, IL1β, and TNFα along with increased expression of IL12, (immunomodulatory cytokine responsible for promoting type 1 immunity) with Uro A treatment (Fig. 1H; Supplementary Fig. S4C).