VEGFA and neoplasm: CSF1R inhibitor inhibits CSF1/CSF1R pathway responsible for TAMs survival. Reduction of ascites in the mouse model of ovarian cancerCombination with PD-1/PD-L1 inhibitor. One patient with ovarian cancer had partial responsePartial restoration of sensitivity to anti-VEGF therapy in mouse xenograft modelReversing TAM phenotype into M1. Reduces tumor growth in mouse model of ovarian cancer