IS: intestinal spirochetosis; N/S: not specified, n: number of persons affected; PCR: polymerase chain reaction, B.A: Brachyspira aalborgi;  B.P: Brachyspira pilosicoli; PB: penicillin benzathine; STD: sexually transmitted disease; U/S: ultrasound; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein. This evidence concerns the gene CRP and sexually transmitted disease.