Univariate analysis for crude odds ratio (OR) was conducted. Neutrophil percentage, lymphocyte (percentage and absolute), eosinophils (percentage and absolute), basophil percentage, TBIL, total protein, A/G ratio, albumin, calcium, phosphorus, sodium, ferritin, LDH, IL-6, CRP/ALB, D-dimer, and fibrinogen were significantly associated with increased severity in COVID-19 patients (Table 6). The gene discussed is IL6; the disease is COVID-19.