In type 2 diabetes patients with or without diabetic retinopathy, multivariate logistic regression analysis showed that APOC2/APOC3 and APOB/non‐HDL cholesterol, as well as APOE/APOC2, were independently related to the risk for the occurrence and severity of diabetic retinopathy.53 This evidence concerns the gene APOC2 and diabetic retinopathy.