According to a large meta-analysis of 11 different studies comprising over 13,000 cases with CAD and controls, ABCG8 and ABO alleles associated with elevated circulating phytosterol levels displayed significant associations with the presence of CAD (rs4245791, OR: 1.10, 95% CI: 1.06, 1.14; rs657152, OR: 1.13, 95% CI: 1.07, 1.19) [75]. Here, ABCG8 is linked to coronary artery disorder.