Furthermore, it was shown that EGCG inhibited the migration and invasion of T24 human bladder cancer cells through the inhibition of the PI3K/AKT pathway that further conferred the inactivation of NF-κB and the down-regulation of MMP-9 expression, ultimately limiting the metastatic potential of the cells [40,42]. The gene discussed is AKT1; the disease is urinary bladder carcinoma.