Several other computational studies have investigated the effects of EGCG on other cancer-related factors including trypsin [263], proteasome [264], PTP1B phosphatase [265], glutathione S-transferase (GST P1-1) [266], or the epigenetic modulators DNMT [267], HDAC [57], and sirtuin-6 (SIRT6) [268], as recently reviewed [269,270]. This evidence concerns the gene SIRT6 and cancer.