TYR and melanoma: On the last topic, and by way of example, Juang et al. [329] took advantage of the fact that the level of tyrosinase, the enzyme that regulates melanin production through melanogenesis, is closely associated with melanoma severity by functionalizing a BODIPY dye with its inhibitor phenylthiourea to improve therapeutic efficacy against a tyrosinase-positive melanoma cell line.