In colorectal cancer cells, oxymatrine inhibited EMT through TGF-β1/Smad and NF-κB pathways [170,171], and in breast cancer cells, oxymatrine suppressed the EMT process via the depressing αVβ3 integrin/FAK/PI3K/AKT signaling pathway [172]. Here, NFKB1 is linked to colorectal cancer.