During the early phase (5–10 days after inoculation), IL-10 seems to be the main player regulating IL-12-dependent IFN-γ production, but after IL-10 levels decrease, there is a substantial production of LXA4, beginning at day 10 and reaching a plateau at day 15 after infection, limiting excessive cytokine production and mortality during a late phase of the infection. Here, IL10 is linked to infection.