TSHR and Graves disease: Cepharanthine can block DRβ1-Arg74 receptors and can block T-cell activation through thyroglobulin peptide Tg2098, among others [52], and, as a DRβ1-Arg74 receptor blocker, it is also able to block the expression of TSH receptor peptide through TSHR presentation and T-cell response, which is essential for the treatment of Graves’ disease [51].