GABRA2 and alcohol dependence: Another meta-analysis has linked alcohol dependence with the gamma-aminobutyric acid A receptor a2 gene (GABRA2), explaining the inhibitor effect of alcohol on GABAergic transmission in the ventral tegmental area (VTA, heterogeneous brain structure with a central role in reward-seeking and processing, learning, motivation, and neuropsychiatric disorders [15]) of the brain [43].