Gaucher disease (GD—OMIM #230800), one of the most prevalent lysosomal storage disorders, is caused by the deficient activity of glucocerebrosidase enzyme (GCase EC 3.2.1.45) due to biallelic pathogenic variants in the gene encoding the acid β-glucocerebrosidase protein, GBA1 (GRCh37/hg19 Chromosome 1: 155,204,239 to 155,214,653). This evidence concerns the gene GBA1 and Gaucher disease.