MRPL58 and colorectal carcinoma: Table 1 provides an overview of the datasets. Specifically, DS1 and DS2 contained 111 and 69 samples, respectively, with a mix of CRC and normal tissue samples, while DS3 comprised 698 samples consisting of primary solid tumor and solid tissue normal samples. Following data preprocessing, a total of 13,051, 20,283, and 16,724 genes were retained for downstream analysis in DS1, DS2, and DS3, respectively. Notably, DS3 combined data from TCGA-COAD and TCGA-READ, and Figure 3 illustrates that the samples in DS3 were closer to each other after applying the batch effect correction.