We recently developed a multiplex diagnostic kit, QPLEXTM Alz plus assay kit, which captures amyloid-β1-40, galectin-3 binding protein, angiotensin-converting enzyme, and periostin simultaneously using microliters of peripheral blood and utilizes an optimized algorithm for screening Alzheimer’s disease (AD) by correlating with cerebral amyloid deposition. The gene discussed is POSTN; the disease is Alzheimer disease.