CLECL1 and myeloid sarcoma: Investigational inference may be derived from a recent genome-wide analysis mapping the X chromosome from 47,429 MS patients, which demonstrated that gene variants for MS susceptibility were enriched in human microglia, along with peripheral immune cells that include the C-type lectin-like protein (CLECL1), as an example [39].The CLECL1 protein is important for self-recognition, with its 20-fold reduction in MS cortical tissue highlighting that microglia may be central to autoimmune-dependent demyelination.