Median serum IL-36β levels in AD patients were 282.9 [13.4–944.4] pg/mL, which tended to be higher than those in healthy controls (141.3 [20.4–437.1] pg/mL), but no statistically significant difference was found between them (p = 0.12; Figure 2A). The gene discussed is IL36B; the disease is Alzheimer disease.