Figure 1B,C show the distinct and continuous membranous staining for PD-L1 and PD-L2 of the tumor cells. In contrast, lymphocytes and macrophages of the TME of tumor tissues from patients with grade 1 stage 1 ((invasive endometrioid adenocarcinoma) node-negative EC with 32% myometrial invasion, LVI absent, and pT1a) were discretely positive for both PD-L1 and PD-L2 (Figure 1E–H). Figure 1I shows PD-1 positivity in lymphocytes in the same patient. Here, CD274 is linked to neoplasm.