AKT1 and neoplasm: Yang et al. [12] showed that resveratrol in combination with cisplatin synergistically inhibits the viability of MDA231 breast cancer cells, as well as their migration and invasion in the MDA231 xenograft model, probably by modifying epithelial to the mesenchymal transition (EMT) program and through the regulation of PI3K/AKT, Smad, NF-B, JNK, and ERK expression in tumour tissue.