Immunohistochemical staining intensity presented as units (BN value) of HIF-1 in tumour tissue of these groups was as follows: 10.6 ± 1.0 (Res + Cis), 20.7 ± 6.3 (Cis + HT), and 32.8 ± 3.0 (Res + Cis + HT), while the staining intensity in the tumour Control tissue was 110.5 ± 5.6 units (Figure 13b). This evidence concerns the gene HIF1A and neoplasm.