Additionally, the SOX9-based 9-gene panel (SOX9, GSK3A, FZD4, LEF1, DVL1, FZD7, NFATC1, KRT19, and RUVBL1) demonstrated a high level of non-invasive diagnostic performance for CRC (AUC: 0.863) [84]. Here, GSK3A is linked to colorectal carcinoma.