IL6 and B-cell chronic lymphocytic leukemia: Similarly, in the CLL cybrids, there was a significant increase in the expression of IL6 in response to the treatment with ALA (1.6-fold change, p < 0.0001), amla (2.1-fold change, p < 0.0001), melatonin (1.2-fold change, p < 0.001), and resveratrol (2.1-fold change, p < 0.0001) (Figure 5).