Similar significant increases in TGFβ expression were observed in the CLL cybrid (Figure 6) in response to Ibr + Amla (1.1-fold change, p < 0.0001), Ibr + Mel (1.4-fold change, p < 0.0001), and Ibr + Resv (1.6-fold change, p < 0.0001. This evidence concerns the gene TGFB1 and B-cell chronic lymphocytic leukemia.