In the CLL cybrids, there was significantly increased expression of IL6 in response to the Ibr + ALA (2.6-fold change, p < 0.0001), Ibr + Amla (4.4-fold change, p < 0.0001), and Ibr + Mel (2.8-fold change, p < 0.0001). This evidence concerns the gene IL6 and B-cell chronic lymphocytic leukemia.