The CLL cybrid also had lower expression of SOD2 after exposure to the combinations Ibr + ALA (0.2-fold change, p < 0.001), Ibr + Amla (0.9-fold change, p < 0.001), and Ibr + Mel (0.7-fold change, p < 0.05). The gene discussed is SOD2; the disease is B-cell chronic lymphocytic leukemia.