TRIM28 and viral infectious disease: Previous studies have discovered that TRIM28 posttranslational modification (such as via phosphorylation and SUMOylation) is dramatically altered during virus infection, including the human adenovirus (HAdV) [24], influenza virus [25], human cytomegalovirus (HCMV) [26], kaposi’s sarcoma-associated herpesvirus (KSHV) [27], and merkel cell polyomavirus (MCPyV) [28].