A. membranaceus extract (1) reduces PGs, NO, IL-1β and TNF-α in LPS-stimulated J774 macrophages; (2) decreases LTC4 in A23187-stimulated peritoneal macrophages; (3) inhibits in vivo inflammatory reactions in zymosan-induced peritonitis; and (4) exhibits beneficial effects on asthma features (Figure 10). The gene discussed is TNF; the disease is peritonitis.