APC, β-catenin (CTNNB1), KRAS, BRAF, SMAD4, transforming-growth factor-beta receptor 2, TP53, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit-alpha, AT-rich interactive domain 1A, sex-determining region Y box 9, family with sequence similarity 123B (also known as AMER1), and ERBB2 have been identified as the most common alterations involved in CRC tumorigenesis [9]. This evidence concerns the gene KRAS and colorectal carcinoma.