PROM1 and neoplasm: CAR133-T cells promoted cytotoxicity and production of IFN-γ and granzyme B after co-culture with tumor cell lines that highly expressed CD133 (i.e., SW1990, Hep3B, HT29, DLD1) without any effect towards non-expressing cells (i.e., SW480 and LOVO) when compared with co-culture with mock and untransduced T cells.