The co-expression of CD133 and the sialyl-Thomsen-nouveau antigen (STn), a carbohydrate moiety found on protein markers of CSCs in ovarian cells and which has been connected with the inability to eliminate quiescent cancer stem cells that survive chemotherapy, is believed to be a contributing factor to recurrent ovarian cancer and tumor recurrence [144]. The gene discussed is PROM1; the disease is neoplasm.