INS and steatosis: In conclusion, combining the analysis of the anthropometric measures and the metabolic profile with the circulating levels of CK18M30 and CK18M65 fragments and the evaluation of liver indices of steatosis and fibrosis, we showed direct associations between both circulating levels of CK18M30 and CK18M65 fragments and visceral obesity, insulin resistance, transaminases, liver stiffness, and APRI.