Using commercially available kits, they are detectable in the blood of iDILI patients as circulatory mediators such as the cytokines IL-22, IL-22 binding protein (IL-22BP), IL-6, IL-10, IL 12p70, IL-17A, IL-23, IP-10, or chemokines like CD206 and sCD163; examples were patients with the diagnosis of suspected iDILI by anti-tuberculosis drugs and verified by the prospective use of the updated RUCAM that provided high causality gradings [123]. This evidence concerns the gene IL22RA2 and tuberculosis.