LINC02544 is overexpressed in lung squamous cell carcinoma patients with lymph node metastasis, and it promotes proliferation, migration, and invasion in vitro by sponging miR-138-5p—a potential target of E2F3 [91]; increased expression of LINC02544 has also been related to in vitro invasion and unfavorable prognosis in breast cancer [92]. This evidence concerns the gene E2F3 and metastatic malignant neoplasm in the lymph nodes.