MIR205HG promotes lung squamous cell carcinoma [48], osteosarcoma [49], melanoma [50], cervical cancer [51,52], head and neck squamous carcinoma [46], and esophageal squamous carcinoma [53]; however, in esophageal adenocarcinoma, it is downregulated and hinders HNRNPA0 mRNA translation by interacting with LIN28A [54] and affecting the Hedgehog pathway [55]. The gene discussed is LIN28A; the disease is osteosarcoma.