NR2F2-AS1 and RPH3AL-AS1 were both downregulated in EOC in comparison with healthy tissues in four independent studies (NR2F2-AS1 was also downregulated in EOC cell lines) and in one study of metastatic tumors, correlating with a favorable prognosis (specifically, with improved disease-free survival), as shown in Figure 8. This evidence concerns the gene RPH3AL and metastatic neoplasm.