FBN1 and colorectal cancer: PGM5-AS1 (ENSG00000224958) is downregulated in both EOC patients and EOC cell lines; it is also downregulated and negatively correlated with oxaliplatin resistance in colorectal cancer [66] but, on the other hand, it is upregulated and sponges miR-140-5p to prevent FBN1 mRNA degradation in osteosarcoma [67].