HAMP protein levels in the renal cortex homogenates detected by ELISA were significantly increased in SCD compared to control mice (Figure 4C, 148.80 ± 30.41 ng/mg protein in SCD vs. 8.12 ± 0.01 ng/mg protein in control, p = 0.0001). Here, HAMP is linked to Schnyder corneal dystrophy.