AKT1 and breast cancer: Among the top ten significant signaling pathways are pathways involved in ‘MicroRNAs in cancer’ with twelve of the fifty-six genes involved, ‘MAPK signaling pathway’ with nine genes, ‘Ras signaling pathway’, ‘PI3K-Akt signaling pathway’ both with eight genes, ‘Breast cancer’ with seven genes, and ‘Cellular senescence’ with six genes (Figure 4).